![]() ![]() One of the most popular and the Best To Do List Chrome Extension for being free (even with payment plan) and having many options is Wunderlist. Remember essential deadlines with reminders and due dates. Do more with Todoist for desktop and mobile devices:Ĭapture and organize your tasks as soon as they appear in your mind. Simply open a new tab with the “New Tab Todo List” Chrome extension to record your ideas, goals, and daily tasks. New Tab Todo List: Checklist, Notes, OutlinerĬreate Escucha, outlines, tasks, and more. Rather basic, but more than enough for the average user. The any.do To Do List Chrome Extension for Chrome of the well-known service Any.do places the list of tasks in a button directly on the toolbar.īeing able to create them from there even with a deadline. Use hashtags or names to feature singular errands 4.Add/expel errands or things effectively.Displays the number of things in the rundown.The number of items remaining in the list is also shown. Simply enter your tasks and rearrange them as you wish using drag & drop. The To-Do List allows you to add and remove items or tasks easily. Yes, Google Tasks still exists ! Many will have enough with the official solution but unfortunately forgotten that Google has for our tasks, and there is an official Chrome extension to use it. Its extension displays our projects and tasks from the toolbar, so we don’t have to open your web page. Todoist is another very famous task service, although with free plans somewhat more limited than those of Wunderlist. Complete tasks from the browser: Once you have completed your tasks, cross them out without changing context. Plan your day: Quickly organize your day’s tasks from the extension. Todoist for ChromeĪdd websites as tasks: Add a blog entry to your reading list. Classified as “the best To Do List Chrome Extension at this time” by The Verge, 20 million people use Todoist to organize, plan and collaborate with others on projects, both large and small. ![]() Organize your work and your life with Todoist for Chrome. Let’s see some examples of this in Chrome. If what we want is just that, we have two options: use the web interfaces of those services (provided they are available, of course) or use an extension that integrates the tasks within the browser’s interface.
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![]() Think about whether what happens on the screen makes intuitive sense to you and if you would agree with how the library works and find it easy to use. Look up YouTube videos of people actually using them.Ĭoncentrate on workflow, too. Do you like their built-in sound? Do you like the sound of their rooms? If you don't like the sounds of their rooms, can you find demos that use the close mics so you can hear those? You can always go close mics + external reverb, but only if the close mics are clean enough from room-noise to make that possible. Get the Modern Underscore Bundle HERE - Use Discount Code: BF21MODERNUNDERSCORE Get the Cinematic Composing Tools Bundle HERE - Use Discount Code: BF21COMPOSINGTOOLS Once you have purchased one of the bundles, you will receive your download link for Solo - Boy Soloists within 24 hours via email. Please note that no further crossgrade or pro-rated discounts will apply to the bundles! The library will be free to any customers purchasing one of the two available Black Friday bundle packages and is only going to be available from the 17th of November until December 4th. Solo - Boy Soloists is a powerful storytelling tool that truly shines through its enchanting and emotion-brimming vocals that carry with them a sense of purity and tranquility. Each of two boy soloists instruments have an Aah and an Ooh Legato, as well as Aah and Ooh Sustains. To really celebrate this year’s Black Friday, we decided to play to our strengths in voice and vocal virtual instrument development and introduce "Solo - Boy Soloists" as a free addition to our SOLO product range, which we launched earlier this year.Ī completely new product that we recorded only a few weeks ago in the same recording space as SOLO, this library includes a set of articulations sung by two incredibly talented boy singers from the children's choir in Budapest. Official r/WeAreTheMusicMakers Discord for music discussion: Official r/AudioProductionDeals Discord for plugin and sales discussion: Great music production subreddits to follow: More information on this can be found here ![]() Many of the links here are affiliate links which we make a commission on to help support the continuation of this subreddit. As such, please do not message asking for posting access if you are not a developer or an authorised dealer. All sales are from legitimate sources and the only people permitted to post here besides myself are developers and authorised dealers themselves. This subreddit exists solely for posting deals from plugin developers or authorised dealers. Failure to adhere to the rules will result in being ban from the subreddit. This subreddit is dedicated to getting posting the best deals on audio plugins and hardware available as things go on sale.īecause of the nature of this subreddit, the rules will be strictly enforced. ![]() ![]() With its ever-evolving fame and experience, Adobe Acrobat Pro seems to have grown to become one of the, if not the most advanced and complete PDF-dedicated programs out there, offering vast possibilities to adjust and alter your PDF documents. The interface seems adaptable, modern, which is why we'd be inclined to see it as many things in one package. While there are plenty of functions to sift through, it never is difficult to find what you're looking for. For example, Scan and OCR are placed under the Create & Edit category.ĭocument signature and adjacent actions are placed under Forms & Signatures. These are split into multiple categories, depending on their utility. If earlier we saw it as a PDF hub for multiple users, the same program can also be viewed as a collection of PDF-related tools. ![]() A collection of toolsĪdobe Acrobat Pro has grown to become so many useful things in one solid package. Of course, you'll get the basic tools as well, magnifying glass, printing options, bookmarks, and so on. Options include combining files, signing them with secure keys, filling blanks and organizing pages, adding comments, and most importantly, exporting them to other file formats. Once you open a PDF file, you'll be presented with yet another set of tools. The interface makes it easy for beginners and advanced users to find and use whatever tools or functions are deemed necessary. Of course, you'll need an account to make use of these features. Sharing documents for adjustments, proofreading, and the likes is a breeze. Product Dimensions : 5.44 x 0.69 x 7.5 inches 3.21 Ounces. The idea of a PDF hub seems to suit any environment, not just work-related ones. Once you launch it, the application will present you with a list of recently opened PDF documents, be these locally, on your PC, or online from Adobe's cloud service. This is the very core from which it has departed in terms of functionality. A PDF hubįirst and foremost, this application is a PDF reader. Protect and assign to certain portfolios, making sure to increase your productivity in the most professional way possible. Deal with PDF files in any imaginable way. Still, Adobe Acrobat Pro comes to prove that there's always room for better. The idea that this application has evolved into one of the most complete PDF-related experiences would be an understatement. You can then save the file to the desired location.At this point in time and space, you can't really deal with PDF files and not have heard of Adobe Acrobat. Then, click the File menu, select Export To, and choose Microsoft Word.” Finally, select Word Document. If you have Adobe Acrobat Pro, you can use it to export any PDF as a Word document. ![]() To download the PDF as a Word document, click the File menu, select Download, click Microsoft Word, and then click Save. Click the Open With menu at the top and select Google Docs. When the upload is complete, Google Docs will display a preview. Click the small folder icon at the top-right corner of the file list, click Upload, select the PDF, and then click Open to upload it. In your web browser, navigate to and sign in with your Google account. But, if the PDF contains images, they may be lost during the conversion. Adobe - Acrobat Pro 2020 Student And Teacher Edition - Mac OS Digital Model: ADO951800V518. Rating 4.6 out of 5 stars with 52 reviews (52) Compare. If you don't have Word, you can use Google Docs to convert a PDF for free. Adobe - Acrobat Pro 2020 Student And Teacher Edition - Windows Digital Model: ADO951800V519. Choose a location to save the file, make sure the ""Word Document"" option is selected as the file format, and then click Save. (The trial version includes all desktop features of Acrobat Pro DC, plus a limited set of Acrobat online. While you can get a free trial version, it will expire and keep you from using the program until you pay for it. Some of the major disadvantages associated with this application are its overall cost and large size. Completely reimagined PDF tools let you create, edit, sign, and track PDFs from. Adobe Acrobat Professional will then transform this data into a PDF form that you can fill out and submit or use online. ![]() Follow the on-screen instructions to sign in and install. All-new Adobe Acrobat Pro DC with Adobe Document Cloud services is here. Edit the file as needed, click the File menu, and select Save As. Click Start your free trial below to begin downloading a trial version of Acrobat Pro DC software on your computer. If you downloaded the PDF from the internet, click Enable Editing at the top of the file and then click OK. Click OK to allow Word to change the display format. ![]() If you have MS Word, right-click the file on your computer, select Open with, and then select Word on the menu. You can use Microsoft Word, Google Docs, or Adobe Acrobat Pro to convert a PDF file into an editable document. ![]() ![]() ![]() Legal status ĭue to deaths linked to ephedra-containing dietary supplements and the potential use of ephedrine as a precursor in illegal methamphetamine manufacture, many countries have taken steps to regulate these products. The stack's effect on the central nervous system results in increased aerobic exercise performance, measured as time until exhaustion relative to respiratory metrics. The stimulating effects of caffeine and ephedrine are an additional contributing factor to weight loss. An estimated 75% of the efficacy of the ECA stack can be attributed to decreased appetite, while the remaining 25% is due to the thermogenic effects of the stack. However, the anorectic effect becomes less pronounced over time, as the body becomes tolerant of ephedrine to some degree. Īdditionally, Ephedrine acts as an anorectic, or appetite-suppressing drug. Aspirin inhibits prostaglandin production outside of the cells, which, in conjunction with caffeine, greatly prolongs the thermogenic effects and increased metabolism by sustaining elevated cAMP levels. It also binds with and competitively inhibits adenosine receptors in the brain, triggering the release of epinephrine and increasing cAMP levels further. Caffeine inhibits the production of phosphodiesterase inside the cell and therefore slows the degradation of cAMP. Adenosine release in the brain additionally speeds the breakdown of cAMP. This takes the form of elevated phosphodiesterase enzyme activity within the cells, as well as prostaglandin release in the synaptic junctions both of these degrade cAMP and mitigate the thermogenic effects. However, the body's negative feedback systems quickly activate to normalize metabolism. This causes a thermogenic effect, raising bodily heat production and increasing energy consumption in conjunction with the rest of the stack. Increased circulating norepinephrine in the body then acts on brown adipose tissue and skeletal muscle by increasing cyclic adenosine monophosphate (cAMP) levels. Ephedrine acts both as an α and β adrenergic agonist, stimulating the release of norepinephrine. The effects of the ECA stack on weight loss are primarily due to the ephedrine component. However, this dosage has not been recommended by regulatory agencies such as the FDA and do not take into consideration mitigation of adverse side effects. More serious adverse effects from ephedra use cannot be excluded at a rate less than 1.0 per thousand, and case reports raise the possibility that a causal relationship with serious adverse events may exist." Dosage Ĭlinical trials indicate that the most effective dose is approximately 20mg of ephedrine and 200mg of caffeine, while the most effective dose of aspirin has not been well-studied. A 2003 meta-analysis of all available studies and case reports concluded that: "ephedrine- and ephedra-containing dietary supplements have harms in terms of a 2- to 3-fold increase in psychiatric symptoms, autonomic symptoms, upper gastrointestinal symptoms, and heart palpitations. Natural supplements that contain ephedra (aka Ma Huang) as an ephedrine substitute have been linked to cases of heart attack, stroke, and death in healthy young adults even when taken at the labeled dosage. There is insufficient evidence to support use of ephedra for athletic performance. A meta-analysis combining results from all available studies estimated average weight loss of 1 kg/month more than placebo. Placebo-controlled studies have consistently found ephedrine in combination with caffeine to be effective in promoting moderate fat loss in the already- obese. While it was available as a supplement, ECA was marketed with claims that it would aid weight loss, improve athletic performance and increase energy. Dietary supplements based on or including elements of ECA were popular through the 1990s and early 2000s, but the marketing of ephedra- or ephedrine-containing stimulant combinations for weight loss and bodybuilding is now restricted or illegal in the United States,and the Netherlands due to reports of heart attack, stroke, and death associated with these supplements. ECA is an initialism for ephedrine, caffeine, and aspirin, with variants of it including the EC stack, which removes the aspirin for those who can not tolerate it. The ECA stack is a drug combination used in weight loss and as a stimulant. Drug combination used in weight loss and as a stimulant ![]() ![]() ![]() Using KOMPLETE KONTROL, everything is collected into a single browser â making flicking through folders and searching for sounds a thing of the past. Thanks to, you now have over a million loops and samples to discover, too. ![]() ![]() Find Sound Faster The KOMPLETE KONTROL software makes browsing easier by organizing and tagging all your KOMPLETE and NKS instruments and effects, allowing you to hear each preset as you scroll. If you want to make tracks on the go, or create a compact studio setup â you now have the perfect keys to fit your needs. Easy to set up, easy to pack away â it doesnât just fit your workflow, but your lifestyle, too. When I set it to Track instance it doesn’t help either, but I can control Cubase 12 with the M32 functions just fine. When I’ve assigned knobs (move a control on the midi controller), the knobs won’t move and the way around. KOMPLETE KONTROL M32 is perfect to plug in and play anywhere. Sadly the M32 Kontroler is not working with the new Cubase 12 midi remote function. Feature Heavy, Travel Ready Inspiration can happen at any moment, so you need to get your ideas down quickly, wherever you are. Combined with innovative software, Smart Play features, and seamless integration, you get intuitive control over all your instruments, effects, loops and samples â directly from your keyboard. Its 32 great-feeling keys not only give you great playability, but also a compact way to express your creativity. Smallest Keyboard Yet KOMPLETE KONTROL M32 has everything you could ask for when making music. ![]() ![]() ![]() Mister Terrific played an important role in Justice League: Unlimited, serving as the team's genius inventor and reliable member. Justice League: Unlimited, the successor series to Justice League and the final entry to the expansive DC Animated Universe. 2.) Justice League Unlimited Mister Terrific Instead of the Shayera Hol version, the live-action reboot's iteration will be Kendra Saunders, set to be played by Isabel Merced. The DCU's version of Hawkgirl is not the same one from the animated series. The DC heroine's most prominent storylines from the show are the Thanagarian invasion (where she played an important role on both sides) and her romance plot with John Stewart aka Green Lantern. In the series, Shayera Hol aka Hawkgirl is one of the founding members of the team and a former member of the Thanagarian military. The show's Justice League consists of Superman, Batman, Wonder Woman, Green Lantern, Flash, Hawkgirl, and Martian Manhunter. Justice League is an animated series from Cartoon Network that is part of the DC Animated Universe. ![]() This comes after the announced castings for the upcoming DCU reboot movie. "Never too early to start doing your homework. ![]() Max recommended four DC shows to watch as "homework" before Superman: Legacy: 4 DC Shows to Watch Before Superman: Legacy Moreover, four new actors were also recently announced to join the Superman reboot movie. In fact, David Corenswet and Rachel Brosnahan have already been tapped to play Clark Kent/Superman and Lois Lane respectively. Superman: Legacy has been on a casting spree lately, with DC Studios slowly assembling its stellar cast. DC just revealed which TV shows fans need to watch ahead of James Gunn's Superman: Legacy. ![]() ![]() Most stings are from honeybees or yellow jackets.Key points about insect stings in children See an allergist for allergy testing and treatment.Make sure your child wears long-sleeve shirts and long pants when playing outdoors.Tell your child's school and babysitters about the allergy and what to do if your child gets stung.These products are available by prescription. ![]() Have your child carry a bee sting kit such as EpiPen at all times and make sure your child knows how to use it.If your child has a known or suspected allergy to stings, follow these tips: Stay calm and walk away slowly if an insect comes near.Stay away from areas that have hives and nests.Use an insect repellent made for children.Not use perfumes, hairsprays, or other scented products.The following are general guidelines to help reduce the chances of insect stings. What can I do to prevent insect stings in my child? An allergic reaction can cause death if the reaction is serious enough and your child does not get medical care right away. The two greatest complications from insect stings are allergic reaction and infection. What are the possible complications of insect stings in a child? Medicines such as epinephrine, antihistamines, or corticosteroids.Watch your child closely for the next hour for signs of a serious allergic reaction.Ĭall 911 and seek emergency care right away if your child is stung in the mouth, nose, or throat area, or if your child has signs of a serious allergic reaction.Be sure to follow dosage instructions carefully for your child. Give an over-the-counter antihistamine, if approved by your child's healthcare provider.Give your child acetaminophen for pain. ![]()
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![]() ![]() The SLNB technique is a highly selective approach based on the finding that tumor cells migrating from a primary tumor metastasize to one or a few lymph nodes before involving other lymph nodes. In the management of breast cancer, a sentinel lymph node biopsy (SLNB) has become standard care for staging axilla in breast cancer patients with clinically negative axillary lymph nodes. A lymphoscintigraphy can identify SLNs at their new unpredicted location. A re-SLNB is precise and beneficial even though there are few patients. This leads to the necessity of using a radionuclide (lymphoscintigraphy) for a successful re-mapping procedure. ConclusionsĪltered lymphatic drainage incidence increases following breast-conserving surgery for an initial breast cancer, and the location of SLNs becomes unpredictable at the time of a second primary or recurrent ipsilateral breast cancer. In one patient, mapping was unsuccessful and the SLN was not identified. The second previously ALND patient had an internal mammary SLN. In one of the two patients, metastases were found in an aberrant lymph drainage basin at the location of a non-ipsilateral axillary node (contralateral axillary SLN). An altered distribution of lymph nodes was discovered in both patients with previous ALND. Localizations of SLNs were ipsilateral axillary in three patients, ipsilateral internal mammary in one patient, and contralateral axillary in two patients. SLNs were successfully remapped in six of seven (85.7%) patients, of whom five (71.43%) had previously undergone SLNB and two (28.57%) previous ALND. Preoperative lymphoscintigraphy was performed four hours before surgery. A dual mapping method was used for all patients. Two of these seven patients had axillary lymph node dissection (ALND) during previous treatments and five had SLNB. Seven patients with either a second primary cancer in the same breast or recurrent breast cancer were described. A lymphoscintigraphy procedure was performed on 330 patients for sentinel lymph node (SLN) mapping on the day of surgery. Methodsīetween March 2006 and November 2013, 458 patients were subjected to a breast SLNB. It evaluates potential reasons for mapping failure that might be associated with patients in this group. This study explores whether a SLNB for patients with primary or recurrent breast cancer is possible after previous axillary surgery. The efficient evaluation of lymphatic drainage of re-sentinel lymph node biopsies (re-SLNBs) has remained a challenge in the management of ipsilateral primary or recurrent breast cancer patients who are clinically lymph node negative. If melanoma has spread to the sentinel lymph node, the other nodes in this area are surgically removed to be certain they do not contain additional melanoma cells.In patients with recurrent or second primary ipsilateral breast cancer, axillary staging is the key factor in locoregional control and a strong prognostic characteristic. Special stains also are used to help visualize even a tiny number of cancer cells. Each slice is examined under a microscope for melanoma cells. The node is removed and sent to a pathologist who slices it into multiple pieces. The presence of the blue dye and an instrument that detects radiation allow the surgeon to identify the sentinel node. A small incision is made near the sentinel lymph node. Like the radioactive material, the dye also drains by lymphatic channels to the sentinel node. To help view the sentinel node during the operation, the surgeon injects a blue dye into the skin around the melanoma. A body scan done several minutes after the injection identifies the sentinel node's position. ![]() ![]() The radioactive substance travels through the lymph channels and collects in the sentinel node. To determine the location of the sentinel node or nodes before surgery, a radioactive material is injected into the skin around the site of the original melanoma. Sometimes there is more than one sentinel lymph node. In some melanomas, tumor cells can travel in more than one direction within the lymph system. ![]() The path of the initial lymph drainage and extent of tumor spread can be determined by locating the sentinel lymph node - the first node that filters lymph fluid draining from the melanoma. Unless the lymph nodes are enlarged and visible during the physical exam or on imaging tests, the only way to accurately determine whether cancer has spread to the lymph nodes is to remove the lymph nodes. Narrator: The thicker a melanoma becomes, the greater the risk of it spreading into the lymphatic system and lymph nodes. ![]() ![]() ![]() Here, in the absence of photon-shielding O 2/O 3, photolysis and/or photo(de)excitation reactions are understood to yield reduced (i.e., S 0 or S 8) and oxidised (i.e., H 2SO 4) sulfur phases that carry positive and negative ∆ 33S values, respectively 12, 13, 16, 17, 18. 1 and 2) 12, 14, 15, the generation and geological preservation of S-MIF is linked to low atmospheric oxygen concentrations in several ways: Starting with its production, anoxic SO 2 photochemistry remains the only experimentally demonstrated means of creating S-MIF that remotely resembles the geological record 13 (Fig. Manifest as non-zero ∆ 3X-values (“Methods” Eqs. ![]() Kazput Formation, BQ Beasley River Quartzite, CB Cheela Springs Basalt. Reitfontain Member, WR Woongarra Rhyolite, BF Boolgeeda Iron Formation, MB1, 2 the diamictites within the Meteorite Bore Member, KF Koolbye Formation, Kaz. Contrastingly, the persistence of low-magnitude non-zero ∆ 33S values throughout cores T2–T3 has been ascribed to the crustal memory effect, with atmospheric oxygenation occurring much earlier (blue horizontal bar, e, Supplementary Information). The subsequent blue horizontal bars in panel c mark isolated instances of S-MIF within the Timeball Hill Formation (TBH) that have been interpreted to represent returns to an anoxic atmospheric state ( Supplementary Information). ![]() The lowermost horizontal blue band in c, d corresponds to the apparently sustained presence of mass-independent sulfur isotope fractionation (S-MIF) within the Rooihoogte Formation (Ro(oi)) seen throughout the Carletonville area 22, 25, 30, 37. Each of the chronologically constrained lithostratigraphic columns follow those presented with the ∆ 33S data 22, 25, 30, 32, 33, with the superimposed vertical grey bars illustrating the ☐.3‰ threshold for identifying S-MIF by ∆ 33S alone 25. Stratigraphic distributions of ∆ 33S data from the South African Kaapvaal ( c core EBA-2 d core KEA-4) and Western Australian Pilbara ( e cores T1–T3) cratons, whose discrepant interpretations have led to the emergence of conflicting models of atmospheric oxygenation. Triangular and circular points represent spot and bulk ∆ 33S analyses respectively. The grey box locates the interval over which atmospheric oxygen is thought to have first accumulated, while the horizontal bars illustrate more traditional redox indicators, whose red and blue colouration discriminates between those disclosing oxic and anoxic conditions, respectively 4, 5. b The secular evolution of ∆ 33S values compiled herein (Supplementary Data File 1). Importantly, these apparent atmospheric relapses were fundamentally different from older putative oxygenation episodes, implicating an intermediate, and potentially uniquely feedback-sensitive, Earth system state in the wake of the Great Oxidation Event.Ī A schematic representation of competing ideas surrounding the oxygenation of Earth’s atmosphere 1 contextualised within a framework of biological innovations. Accepting others’ primary photochemical interpretation, our approach demands that these implied atmospheric dynamics were ephemeral, operating on sub-hundred-thousand-year timescales. Next, utilising statistical approaches, supported by new MSI data, we show that the reconciliation of adjacent, yet seemingly discrepant, South African MSI records requires that the rare instances of post-2.3-billion-year-old S-MIF are stratigraphically restricted. Herein, however, after accounting for unrecognised temporal and spatial biases within the Archaean–early-Palaeoproterozoic MSI record, we demonstrate that the global expression of the CME is barely resolvable thereby validating S-MIF as a tracer of contemporaneous atmospheric chemistry during Earth’s incipient oxygenation. Nevertheless, S-MIF recycling through oxidative sulfide weathering-commonly termed the crustal memory effect (CME)-potentially decouples the multiple sulfur isotope (MSI) record from coeval atmospheric chemistry. Given its origin in oxygen-free photochemistry, mass-independent sulfur isotope fractionation (S-MIF) is widely accepted as a geochemical fingerprint of an anoxic atmosphere. Understanding the timing and trajectory of atmospheric oxygenation remains fundamental to deciphering its causes and consequences. ![]() |
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